Artificial Polymeric Cornea Project
The overall goal of this project is to develop a new synthetic/hydrogel artificial cornea with a high degree of biocompatibility, which is also easily implantable and cost-effective.
An artificial cornea will alleviate the issue of tissue shortage and will help the estimated 10 million people worldwide who are blind from corneal diseases. It will also benefit those patients for which traditional human
corneal transplantation does not work, such as patients with severely dry eyes, chemical burns, and multiple corneal graft failures.
Methods of modern chemistry will
be used to develop polymers with important
characteristics for a successful artificial cornea, such as biocompatibility, flexibility,adequate mechanical strength, allowance for nutrient transport, and support of surface epithelial cell growth.
This project will use an interdisciplinary approach involving ophthalmology, polymer chemistry, biochemistry, cell biology ,pharmacology,and pathology.