Chitin & Chitosan Derived from Shrimp’s Shell of Persian Gulf

Biopolymers with no toxicity, biodegradable and biocompatible with several ten of applications

 

What are Chitin and Chitosan?

Chitin is one of the most abundant polysaccharides found in nature. It is found naturally in the shells of crustaceans, insect exoskeletons, fungal cell walls, micro fauna and plankton. It is found in association with proteins and minerals such as Calcium Carbonate. Chitosan is a useful derivative of chitin. It is formed through N-deacylation of the chitin molecule.

Applications

Chitin and Chitosan have several applications in the following fields:

Agricultural, Cosmetics, Medicinal, Food Industry, Dentistry, Drug Delivery System, Biomaterials, Wound Healing, Burn Treatment, Cell Binding Activity of Chitin, Chitosan as a Hemostasis Agent, Cancer and Fracture Healing, Artificial Skin, Contact Lens, etc...

Chitin was extracted at Iran Polymer & Petrochemical Institute from Persian Gulf shrimp’s shells. This powder is being named as Persian Gulf Chitosan (PGC). The key parameters obtained from the elemental analysis are shown in the below table. The degree of deacetylation (DD) is determined from the nitrogen percent of the Chitosan samples.

DD of PGC was 90-99% and MV around 1.03-5.31×105 .

 

Chitosan

DD%

MV  ×105

PGC-1

93.33

1.03050

PGC-2

93.33

2.9015

PGC-3

90

3.9492

PGC-4

93.33

3.8255

PGC-5

90

3.9689

PGC-6

99

4.6573

PGC-7

96.67

5.3158

PGC-8

98.34

4.1126

 

 

The purity of PGC is unique and IPPI now is a provider of the pure Chitin and Chitosan.

References:

1. N.Yaghobi, H.Mirzadeh, et al, Optimization of Chitin Isolation from Shrimp Shells: Study of parameters Influence on Chitin Deacetylation Reaction and Biocompatibility Evaluation (in vitro) Iranian Journal of Polymer Science and Technology 15, 55-63, 2002.

 2. H.Mirzadeh, N.Yaghobi, et al, “In vivo Study of Microcrystalline Chitosan as a Blood Hemostasis Agent, International Conference on Materials for Advanced Technologies (ICMAT 2001) Symposium B, Biomaterials and Tissue Engineering, (1-6 July 2001), Singapore.

3. H. Mirzadeh, N.Yaghobi, et al, Preparation of Chitosan Derived from Shrimp’s Shell of Persian Gulf as a Blood Hemostasis Agent: In vivo, Iranian Polymer Journal, 11, 1 63-68, 2002.

4. N. Yaghobi, H. Mirzadeh, et al, Deacetylation of Chitin by Multistage alkali treatments, Submitted to the Iranian Polymer Journal (2202).

5. H.Mirzadeh, et.al, Poly vinyl alcohol /Chitosan Blends: Preparation, Mechanical and Physical Properties, Submitted to the Iranian Polymer Journal (2002).

 

For more information contact: N.Yaghobi@ipi.ac.ir

www.iranpolymerinstitute.org

 

Figure: PGC Pilot Plant  at IPPI.