CURRICULUM VITAE

HAMID MIRZADEH (PhD, MSc, BSc)

Professor

PERSONAL INFORMATION 

Hamid Mirzadeh
Professor at Amirkabir University of Technology (Tehran Polytechnic)
Head of Iran Polymer and Petrochemical Institute
Editor-in-Chief, Iranian Polymer Journal
Director of Iran Polymer Society
Address 1: Tehran (Postal Region: 14, Postal Code: 14977 13115)
Km 15 Tehran-Karaj Highway, Exit 17 Pajouhesh Blvd.
P.O.Box: 14965/115 Tehran, Iran.
Tel: + 98 21 44580020; Fax: + 98 21 44580021
Address 2: Amirkabir University of Technology ( Tehran Polytechnic)
Faculty of Biomedical Engineering, 
Hafez Ave, P.O.Box: 15875/4413,Tehran, Iran.

http://www.iranpolymerinstitute.org/resume/bmhm.htm

Email:  H.Mirzadeh@ippi.ac.ir

Languages: Persian, English, and Arabic

EDUCATIONAL INFORMATION

New South Wales University, Sydney, Australia, PhD, Chemical Engineering 1990-1993

Amirkabir University (Tehran Polytechnic), Tehran, Iran, MSc., Polymer Science and Technology 1976-1978

Ferdosi, University, Mashhad, Iran, BSc. Chemistry 1969-1972

POSITION HELD

Kerman University Research Associate and lecturer 1979-1985

Iran Polymer & Petrochemical Institute (IPPI) Research Associate1985-.

Iranian Journal of Polymer Science & Technology (ISSN: 1016-3255, Persian Edition) Editor-in-Chief 1985-.

Iranian Polymer Journal (ISSN: 1026-1265, English Edition) Editor-in-Chief.1990-.

Laser Research Center of Iran Research Associate 1991-..

Head, Department of  Polymeric Biomaterial at IPPI 1993-.

Amirkabir University of Technology, Assistant Professor of  Faculties of  Polymer Eng. and Biomedical Eng.1994-.

Amirkabir University of Technology, Associate Professor of  Faculties of  Polymer Eng. and Biomedical Eng.1999-

Iran Polymer  and Petrochemical Institute, Director 1999-.

Amirkabir University of Technology, Professor of the Faculties of Polymer Eng. and Biomedical Eng. 2004-.

Editor- in- Chief,   Iranian Polymer Journal ,1992-. (A Distinguished International Journal, 7th National Festival Award, 2007.)

COURSES TAUGHT

At Amirkabir University of Technology (Tehran Polytechnic), Faculties of Biomedical Engineering/Polymer Engineering:

      ·        -Methods & Principles of Tissue Engineering, 3 units

      ·        -Biocompatibility Issues, 3 units (1 unit workshop)

      ·        -New Techniques for Biomaterials Surface Analysis, 3 units (1 unit workshop)

      ·        -Polymers in Medicine, 3 units (1unit workshop)      

SCHOLARSHIP & AWARDS

·        MSc Amirkabir University of Technology ( Tehran Polytechnic)

·        PhD (New South Wales University), 1991-1994.

·        8th Kharazmi International Festival Award (Ministry of Science and Higher Education of Iran), 1994.      

·         Distinguished Professor of Amirkabir University of Technology,  2004.

·         9th Razi Research Festival on Medical Sciences Award,  , 2004.

·         Distinguished Professor of Iran Polymer and Petrochemical Institute, 2005.

·        12th  Razi Research  Festival on Medical Sciences Award,  2007.

·         Distinguished Director of Iran Research and Technology Centers, 7th National Festival Award, 2007.

·        13th  Razi Research  Festival on Medical Sciences Award,  2008.

NATIONAL  RESEARCH COUNCIL  (NRC) PROJECTS

·        Design and Manufacturing of Polymeric Biomaterials, in vitro and in vivo assays, National Research Council, Project No. 5862, 1998-2001.

·        Design and Fabrication of Cochlear Implant, in vitro and in vivo assays, National Research Council, Project No. 0168, 1998-2001.

AREA OF INTEREST

The main present fields of research at our department are focused on polymeric biomaterials design and preparation, biopolymers used as scaffold for tissue engineering ,  morphological studies of the polymer surfaces, analysis of polymer blends and copolymers as well . Laser induced surface modification of polymers to improve biocompatibility is the other current activities in our department. We have applied FT-IR, ATR-FT-IR, UV-visible laser beam, x-ray diffraction measurements, electron spectroscopy for chemical analysis (ESCA), scanning electron microscopy (SEM), energy dispersive x-ray analysis and dynamic mechanical thermal analysis (DMTA) , surface charge measurements ( zeta potential) and  surface tensiometry to characterize the bulk and surface properties of  biomaterials. We are interested in drug delivery systems using biodegradable polymers specially injectable implant delivery system, as in situ forming for release of drugs/agents  including radioisotopes ( local cancer therapy), corticosteroide and contraceptive drugs. Another our research efforts are centered on the development of a better understanding of blood and tissue/material interactions as they relate to implantable devices and biomaterials. Studies currently ongoing include evaluation of the biocompatibility of polymeric biomaterials using in vivo and in vitro assays as well as tissue engineering for bone,  cartilage and skin regeneration  to study the cellular and humeral responses to implanted materials and /or cell seeded onto biodegradable biomaterials. We have introduced a novel technique to create blood compatible materials and investigating human blood/material interaction, protein adsorption, cellular components, coagulation parameters platelet adhesion and activation. Laser-induced copolymerization of acrylated monomers onto the surface of polymers to achieve the new biomaterials generation is the other efforts. We are designed  a special artificial skin using biodegradable biopolymers/polymers. Finally, a biopolymer-biomaterial adhesive for prevention of the blood oozing is one of our recent achievements. The completed/current research at our department are summarized as the following:

 CURRENT RESEARCHES ( CR) OR COMPLETED PROJECTS  (C) 

·        Cartilage Tissue Engineering Using Perforated Polyurethane or Porous Chitosan (in vitro & in vivo Assays). ( CR)

·        Design and in vitro & in vivo Assays of Artificial Skin based on PVA, Collagen and Chitosan Composite.( C)

·        Optimization of Chitosan Porosity and Pore Size Choosing Different Molecular Weight for Tissue Engineering .( C)

·        Fabrication of Porous Polyethylene and Persian Gulf  Coral  as a Biomaterial  for Maxillofacial Surgery Purposes: in vitro.( CR)

·        Design and manufacturing of a Semi-Industrial Pyrocarbon Pilot Plant for Medical Purpose. ( CR)

·        Evaluation of Physical Environment effect  on Chondrocyte cells Seeded onto  Porous and  Biodegradable Polyurethane Scaffolds.( C)

·        Enhancement of E- Coli Adsorption onto PET Film Surface Using Excimer Laser.(C )

·        Preparation and Formulation of Flat and Hollow Fiber Hemodialysis Membrane .( C)

·        Preparation of biodegradable injectable in situ forming polymeric system for internal radionuclide therapy of carcinoma.                       

·        Design and in vitro & in vivo Assessment of Artificial Heart’s Pericardium Membrane.(C) 

·        Tissue Engineering of Artificial Skin Using Laser Treated PDMS and AAc/Collagen blends: in vitro & in vivo . ( CR)

·        Design and in vitro & in vivo Assays of Artificial Vascular Grafts in vitro & in vivo.(C) 

·        Design and in vitro & in vivo Assays of Artificial Cornea using PHEMA//Collagen/PMAAc Blends (C) 

·        Design and in vitro & in vivo Assays of Medical Adhesive composites using PU/Chitosan to Stop Severe Bleeding.(C) 

·        Evaluation of Chitosan Gel as Alveolar Fistula Sealing : in vivo Study.( C)

·        Design and in vitro Assessment of Eye Valve for Glaucoma Treatment.(C) 

·        Biocompatibility Evaluation of RF Plasma Treated Polystyrene, in vitro.( CR)

·        Grafting of Hydrogels by Laser on Polymers in Uses of Biocompatibility and Blood Compatibility.(C) 

·        Preparation of PLGH-Injectable Implant Delivery System, as in situ Forming for Release of Corticosteroidal Drugs: In vitro & in vivo. ( CR)

·        Design and manufacturing of Cryogenic Hydrogels Used in Cold Operational Surgeries and Maintaining the Fresh Cells and Tissues.(C) 

·        Design and manufacturing of O-Ring for Dialysis Filter.(C) 

·        Dynamic Oscillatory Rheology of Gelatin Solution in Different Temperatures.( CR) 

·        Microencapsulation of Cancer Drugs  for Targeting Therapy. In vitro.( CR)                               

·        Contraceptive Agents Release from an In  Situ Forming Drug Delivery System : In vitro.( CR)

·        Design of a Semi-Industrial Production Pilot Plant for Preparation of Chitin and Chitosan of the Shrimps’ Shell of Persian Gulf with high degree of deacetylation ( for chitosan) and Medium Molecular Weight.(C) 

·        Peptide Immobilization onto Laser -Irradiated Polymer Films to Improve blood Compatibility.(C) 

·        Plasma -Induced Graft Polymerization of Acrylamide onto Silicone Rubber.( C) 

·        Design and in vitro & in vivo Assays of Polyester Vascular Grafts Coated with Graphite.(C) 

·        Bone Tissue Engineering Using Chitosan/Gelatin/TCP Porous Scaffolds: In vitro & in vivo Study( CR)

·        UHMWPE/Hydroxy Apatite/PDMS  as Artificial Hip Joint: Design, Manufacturing and Biocompatibility Evaluation. (CR)

·        Preparation and Characterization of Supra- molecular Polymers(CR)

·        Drug Eluting Polymers for Biomedical Applications (CR)

·        Preparation of PEG Based Biodegradable Polymeric Networks with Application in Topical Drug Delivery(CR)

·        Evaluation of Molecular Network Formation of Gelatin and Biomineralized Gelatin for Biomedical Application: Rhehological and NMR Studies (CR)

·        Effect of Formulation Variables on the Design of an Acrylic/Silicone Pressure Sensitive Adhesive System for Transdermal Delivery of Fentanyl(CR)

·        Preparation and Modification of the Surface Properties of PDMS to Immobilize Collagen Cornea Application: in vitro & in vivo(CR)

·        Evaluation of Aphthous Fever Virus Realizing from PLGA Nanoparticles(C)

·        Comparison the Effect of Eximer Laser and RF Plasma on Polystyrene Surface Based on Biocompatibility (C)

·        KrF Laser Induced Nano-Structuring onto Polyethyleneterephtalate ( PET) by Different Repetition Rate : Evaluation of the Biocompatibility of the Treated             surfaces: in vitro(CR)

SCIENTIFIC SOCIETY MEMBER

1.      President, Iran Polymer Society (Founder of the society and member of organizing committee and board).

2.      Iran Chemistry & Chemical Engineering Society (Member).

3.   Society for Biomaterials, USA  (Member).

4. Controlled Release  Society of Iran-CRSI ( Member of the directory of board).

JOURNALS' REVIEWER :

1-Artificial Organs,  Official Journal of ISAO, INFA and ISRP Published by Blackwell.

2- Journal Biochimica et Biophysica Acta (BBA - Biomembranes) Published by Elsevier.

3- Journal of Applied Polymer Science (English), Published by John Wiley & Sons,    Inc.

4- Iranian Polymer Journal (English), Published by the Iran Polymer & Petrochemical Institute (IPPI).

5-Biomacromolecules, Published by ACS Publications.

6- Iranian Journal of Chemical Engineering; (English), Published by the Iranian  Association of Chemical Engineers (IACHE).

7 Iranian Journal of Polymer Science &Technology (Persian), Published by the Iranian  Polymer Society .

8 Iranian Journal of Chemistry& Chemical Engineering (English& Persian), Published by the Jahad Daneshgahi .

9-Journal of Iranian Medical Engineering Society, (Persian).

10-Journal of the Iranian Chemical Society (JICS)

  ACKNOWLEDGMENT

I would like to appreciate my colleagues or students who were participated and cooperated with some parts of my works and publications:

I-Professor M.A. Semsarzadeh, Professor R.P.Burford, Professor A.A.Katbab, Professor P.G. Sammes, Professor N. Sharifi-Sanjani, Professor A.A. Entezami, Prof. H.Ahmadi, Prof. H. Mirkhani, Prof. M.A.Mohagheghi, Dr. S.Amanpour, Dr. M.Daliri, Dr. Sh. Rabbani, Dr. P.Salehian, Dr. R. Sedighi Mr. F. Soltamoradi, Mrs. N.Yaghobi, Mr. F.Hormozi, Dr. M.Mehrabzadeh, Dr. E. Jabbari,  Ms. P.Shokrolahi, Dr. G. R. Bakhshandeh, Mr. B. Sadatnia, Prof. S. Madaeni,  Dr. V. Hadai-Asl ,  Dr. S.SH. Hoseini., Prof. P. Mansouri, Dr. Alireza Ghaffariyeh, Dr. F. Orang , Dr.H.Mobedi ,  Dr.M.Imani.,   A. Abdi., Dr. M.Soleimani, Professor E. Vasheghani Frahani, Professor F. Moztarzadeh,   Dr.  M.R. Baghban Eslaminejad, Dr. H. Yeganeh and Dr. M. Zohorian - Mehr.

II- Dr. M.T. Khorasani, Dr. M.Dadsetan, Dr. N. Shikh, Dr. F. Abbasi, Dr.B.Bahrami, Ms. D. Falahi, Ms. F.Shokrolahi, Mr. A.R. Ekbatni, Mr. M. Rezaee Darvishi, Mr. M.R